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| The antioxidative effects of acidic-, alkalic-, and enzymatic-extractable mycelium zinc polysaccharides by Pleurotus djamor on liver and kidney of streptozocin-induced diabetic mice. | Zhang J, Meng G, Zhang C, Lin L, Xu N, Liu M, Cui F, Jia L. | BMC Complement Altern Med | 10.1186/s12906-015-0964-1 | 2015 | 26683206 | chemistry, drug therapy, administration & dosage, administration & dosage | | |
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| Toxin-Induced Experimental Models of Learning and Memory Impairment. | More SV, Kumar H, Cho DY, Yun YS, Choi DK. | Int J Mol Sci | 10.3390/ijms17091447 | 2016 | 27598124 | Memory, Learning, Cognition, Animal model, Toxin, Dementia, etiology, etiology, toxicity, drug effects, drug effects | Pathogenicity | |
| Gynura procumbens Extract Alleviates Postprandial Hyperglycemia in Diabetic Mice. | Choi SI, Park MH, Han JS. | Prev Nutr Food Sci | 10.3746/pnf.2016.21.3.181 | 2016 | 27752493 | Postprandial Hyperglycemia, Gynura Procumbens Extract | | |
| Protective effects on liver, kidney and pancreas of enzymatic- and acidic-hydrolysis of polysaccharides by spent mushroom compost (Hypsizigus marmoreus). | Liu M, Song X, Zhang J, Zhang C, Gao Z, Li S, Jing H, Ren Z, Wang S, Jia L. | Sci Rep | 10.1038/srep43212 | 2017 | 28233836 | metabolism, drug therapy, prevention & control, metabolism, metabolism, Composting | Metabolism | |
| Long non-coding RNA MIAT acts as a biomarker in diabetic retinopathy by absorbing miR-29b and regulating cell apoptosis. | Zhang J, Chen M, Chen J, Lin S, Cai D, Chen C, Chen Z. | Biosci Rep | 10.1042/bsr20170036 | 2017 | 28246353 | Diabetic retinopathy, High glucose, Cell Apoptosis, Mir-29b, Miat, genetics, genetics, genetics, Apoptosis, Gene Expression Regulation, genetics | | |
| Mycofumigation through production of the volatile DNA-methylating agent N-methyl-N-nitrosoisobutyramide by fungi in the genus Muscodor. | Hutchings ML, Alpha-Cobb CJ, Hiller DA, Berro J, Strobel SA. | J Biol Chem | 10.1074/jbc.m117.779009 | 2017 | 28283571 | Fungi, Toxicity, DNA methylation, Cell death, Endophyte, Mycotoxin, N-nitroso compounds, volatile organic compounds, Gas Chromatography-mass Spectrometry (Gc-ms), Mycofumigation, metabolism, Antifungal Agents, drug effects, drug effects, metabolism, Volatile Organic Compounds | Metabolism | Pathogenicity |
| Berberis vulgaris and its constituent berberine as antidotes and protective agents against natural or chemical toxicities. | Mohammadzadeh N, Mehri S, Hosseinzadeh H. | Iran J Basic Med Sci | 10.22038/ijbms.2017.8678 | 2017 | 28656089 | Berberine, Antioxidant, Anti-inflammation, Antidote, Berberis Vulgaris, Barberry, Natural Toxin, Chemical Toxin | Pathogenicity | |
| Animal Models of Diabetic Retinopathy. | Olivares AM, Althoff K, Chen GF, Wu S, Morrisson MA, DeAngelis MM, Haider N. | Curr Diab Rep | 10.1007/s11892-017-0913-0 | 2017 | 28836097 | VEGF, Diabetes, Diabetic retinopathy, alloxan, STZ, Animal Models, Pancreatectomy, Genetic Models, Induced Models, pathology, Disease Models, Animal | | |
| Elucidation of Molecular Mechanisms of Streptozotocin-Induced Oxidative Stress, Apoptosis, and Mitochondrial Dysfunction in Rin-5F Pancreatic beta-Cells. | Nahdi AMTA, John A, Raza H. | Oxid Med Cell Longev | 10.1155/2017/7054272 | 2017 | 28845214 | metabolism, toxicity, drug effects, drug effects, metabolism, pathology | Metabolism | Pathogenicity |
| Determination of the critical diabetes duration in a streptozotocin-induced diabetic rat calvarial defect model for experimentation regarding bone regeneration. | Kim HJ, Jung BH, Yoo KY, Han JW, Um HS, Chang BS, Lee JK. | J Periodontal Implant Sci | 10.5051/jpis.2017.47.5.339 | 2017 | 29093990 | Diabetes mellitus, streptozocin, Bone regeneration, Cone-beam Computed Tomography | | |
| The benzodiazepine-like natural product tilivalline is produced by the entomopathogenic bacterium Xenorhabdus eapokensis. | Wolff H, Bode HB. | PLoS One | 10.1371/journal.pone.0194297 | 2018 | 29596433 | metabolism, metabolism, metabolism | Metabolism | |
| Taxifolin attenuates diabetic nephropathy in streptozotocin-induced diabetic rats. | Zhao Y, Huang W, Wang J, Chen Y, Huang W, Zhu Y. | Am J Transl Res | | 2018 | 29736213 | Inflammation, Streptozotocin (STZ), Caveolin-1, Taxifolin | Pathogenicity | |
| Genome-Based Taxonomic Classification of the Phylum Actinobacteria. | Nouioui I, Carro L, Garcia-Lopez M, Meier-Kolthoff JP, Woyke T, Kyrpides NC, Pukall R, Klenk HP, Goodfellow M, Goker M. | Front Microbiol | 10.3389/fmicb.2018.02007 | 2018 | 30186281 | Morphology, Chemotaxonomy, G+C content, Genome size, Phylogenetic systematics, Phylogenomics, Genome Blast Distance Phylogeny | Genetics | Phylogeny |
| Identification of a butenolide signaling system that regulates nikkomycin biosynthesis in Streptomyces. | Wang W, Zhang J, Liu X, Li D, Li Y, Tian Y, Tan H. | J Biol Chem | 10.1074/jbc.ra118.005667 | 2018 | 30355730 | Antibiotics, Streptomyces, Signal transduction, Transcription regulation, Receptor, Gene cluster, Molecular genetics, secondary metabolism, Nikkomycin, Butenolide Signaling Molecules, metabolism, analogs & derivatives, metabolism, Biosynthetic Pathways | Metabolism | |
| Polygonatum sibiricum polysaccharide potentially attenuates diabetic retinal injury in a diabetic rat model. | Wang Y, Lan C, Liao X, Chen D, Song W, Zhang Q. | J Diabetes Investig | 10.1111/jdi.12976 | 2019 | 30426692 | Apoptosis, Diabetic retinopathy, Polygonatum Sibiricum Polysaccharide, drug effects, chemistry, prevention & control, complications, pharmacology, drug effects, metabolism | Pathogenicity | Metabolism |
| Differential change in cortical and hippocampal monoamines, and behavioral patterns in streptozotocin-induced type 1 diabetic rats. | Lin LW, Tsai FS, Yang WT, Lai SC, Shih CC, Lee SC, Wu CR. | Iran J Basic Med Sci | 10.22038/ijbms.2018.29810.7197 | 2018 | 30524676 | Mice, Cerebral cortex, Hippocampus, Biogenic amines, Memory And Learning Tests, Oral Glucose Tolerance Test Type 1 Diabetes Mellitus | | |
| Antidiabetic potential of active fraction obtained from methanolic extract of Ichnocarpus frutescens: A possible herbal remedy. | Srujana M, Ramesh R, Nanjaiah LD. | Indian J Pharmacol | 10.4103/ijp.ijp_24_18 | 2018 | 30636828 | Diabetes mellitus, Hepatic glycogen, Glibenclamide, Plasma Insulin, Ichnocarpus Frutescens, chemistry, drug therapy, pharmacology, pharmacology | | |
| An N-nitrosating metalloenzyme constructs the pharmacophore of streptozotocin. | Ng TL, Rohac R, Mitchell AJ, Boal AK, Balskus EP. | Nature | 10.1038/s41586-019-0894-z | 2019 | 30728519 | biosynthesis, chemistry, metabolism | Metabolism | |
| Treatment With Naringenin Elevates the Activity of Transcription Factor Nrf2 to Protect Pancreatic beta-Cells From Streptozotocin-Induced Diabetes in vitro and in vivo. | Rajappa R, Sireesh D, Salai MB, Ramkumar KM, Sarvajayakesavulu S, Madhunapantula SV. | Front Pharmacol | 10.3389/fphar.2018.01562 | 2018 | 30745874 | Apoptosis, Diabetes, Streptozotocin, NRF2, naringenin, Min6 Cells | | |
| Liposomal Curcumin is Better than Curcumin to Alleviate Complications in Experimental Diabetic Mellitus. | Bulboaca AE, Porfire AS, Tefas LR, Boarescu PM, Bolboaca SD, Stanescu IC, Bulboaca AC, Dogaru G. | Molecules | 10.3390/molecules24050846 | 2019 | 30818888 | Catalase, Oxidative stress, Malondialdehyde (MDA), Curcumin, Diabetes Mellitus (DM), Streptozotocin (STZ), Matrix Metalloproteinases (Mmp), Nitric Oxide (Nox), drug therapy, prevention & control, pharmacology, pharmacology, administration & dosage, pharmacology | | |
| Effects of the fenugreek extracts on high-fat diet-fed and streptozotocin-induced type 2 diabetic mice. | Li XY, Lu SS, Wang HL, Li G, He YF, Liu XY, Rong R, Li J, Lu XC. | Animal Model Exp Med | 10.1002/ame2.12004 | 2018 | 30891549 | Diabetes mellitus, hyperglycemia, C57bl/6j Mice, Fenugreek | | |
| A New Way for Beta Cell Neogenesis: Transdifferentiation from Alpha Cells Induced by Glucagon-Like Peptide 1. | Zhang Z, Hu Y, Xu N, Zhou W, Yang L, Chen R, Yang R, Sun J, Chen H. | J Diabetes Res | 10.1155/2019/2583047 | 2019 | 31001561 | metabolism, drug effects, drug effects, pharmacology, drug effects | Pathogenicity | Metabolism |
| The protective effect of Satureja bachtiarica hydroalcoholic extract on streptozotocin-induced diabetes through modulating glucose transporter 2 and 4 expression and inhibiting oxidative stress. | Joudaki R, Setorki M. | Pharm Biol | 10.1080/13880209.2019.1597131 | 2019 | 31060468 | Oxidative stress, Glucose transporter, Diabetes, Streptozotocine, chemistry, drug therapy, therapeutic use, therapeutic use, drug effects, genetics, genetics | Pathogenicity | |
| Evaluating the Impact of Different Hypercaloric Diets on Weight Gain, Insulin Resistance, Glucose Intolerance, and its Comorbidities in Rats. | Melo BF, Sacramento JF, Ribeiro MJ, Prego CS, Correia MC, Coelho JC, Cunha-Guimaraes JP, Rodrigues T, Martins IB, Guarino MP, Seica RM, Matafome P, Conde SV. | Nutrients | 10.3390/nu11061197 | 2019 | 31141900 | Hypertension, Obesity, Adipose tissue, Type 2 diabetes, weight gain, Insulin sensitivity, metabolic syndrome, Animal Models, Glucose Tolerance, etiology, etiology, etiology, Insulin Resistance, etiology, Weight Gain, Dietary Sucrose, Diet, High-Fat, etiology | | |
| Structural and biochemical characterization of Rv0187, an O-methyltransferase from Mycobacterium tuberculosis. | Lee S, Kang J, Kim J. | Sci Rep | 10.1038/s41598-019-44592-7 | 2019 | 31147608 | enzymology, metabolism, metabolism | Metabolism | Enzymology |
| Impact of coxsackievirus-B4E2 combined with a single low dose of streptozotocin on pancreas of outbred mice: investigation of viral load, pathology and inflammation. | Benkahla MA, Sane F, Bertin A, Vreulx AC, Elmastour F, Jaidane H, Desailloud R, Hober D. | Sci Rep | 10.1038/s41598-019-46227-3 | 2019 | 31300658 | pathology, pathology, pathology, pharmacology | | |
| Glucose-lowering and hypolipidemic activities of polysaccharides from Cordyceps taii in streptozotocin-induced diabetic mice. | Liu RM, Dai R, Luo Y, Xiao JH. | BMC Complement Altern Med | 10.1186/s12906-019-2646-x | 2019 | 31443712 | Polysaccharides, Diabetes mellitus, Cordyceps taii, Hypolipidemia, Glucose-lowering Effect, chemistry, metabolism, pharmacology, pharmacology, pharmacology | Metabolism | |
| 1-Palmitoyl-2-Linoleoyl-3-Acetyl-rac-Glycerol Attenuates Streptozotocin-Induced Pancreatic Beta Cell Damage by Promoting Glucose Transporter 2 Endocytosis. | Kim J, Kim JH, Sohn KY, Yoon SY, Kim JW. | Mol Cell Biol | 10.1128/mcb.00157-19 | 2019 | 31481450 | Endocytosis, Streptozotocin, Beta cell, GLUT2, Plag, pharmacology, drug effects, drug effects | Pathogenicity | |
| Loss of interleukin-10 exacerbates early Type-1 diabetes-induced bone loss. | Rios-Arce ND, Dagenais A, Feenstra D, Coughlin B, Kang HJ, Mohr S, McCabe LR, Parameswaran N. | J Cell Physiol | 10.1002/jcp.29141 | 2020 | 31538345 | Osteoblasts, Osteoporosis, Bone, IL-10, Type-1 Diabetes, genetics, genetics, genetics, genetics, genetics | | |
| Network-based method for drug target discovery at the isoform level. | Ma J, Wang J, Ghoraie LS, Men X, Liu L, Dai P. | Sci Rep | 10.1038/s41598-019-50224-x | 2019 | 31554914 | chemistry, methods | | |
| Lack of insulin resistance in response to streptozotocin treatment in neuronal SH-SY5Y cell line. | Bagamery F, Varga K, Kecsmar K, Vincze I, Szoko E, Tabi T. | J Neural Transm (Vienna) | 10.1007/s00702-019-02118-5 | 2020 | 31858268 | Insulin resistance, Neurodegeneration, Streptozotocin, Glycogen synthase kinase-3, Sh-sy5y Cell Line, drug effects, metabolism, Insulin Resistance, pharmacology, pharmacology, pharmacology, pharmacology | Pathogenicity | Metabolism |
| Antibacterial potential of Juglomycin A isolated from Streptomyces achromogenes, an endophyte of Crocus sativus Linn. | Ahmad T, Arora P, Nalli Y, Ali A, Riyaz-Ul-Hassan S. | J Appl Microbiol | 10.1111/jam.14568 | 2020 | 31883416 | Biofilm, Escherichia Coli, Gene Expression, Saffron, Bacterial Motility, chemistry, microbiology, pharmacology | | |
| Shifts Between and Among Populations of Wheat Rhizosphere Pseudomonas, Streptomyces and Phyllobacterium Suggest Consistent Phosphate Mobilization at Different Wheat Growth Stages Under Abiotic Stress. | Breitkreuz C, Buscot F, Tarkka M, Reitz T. | Front Microbiol | 10.3389/fmicb.2019.03109 | 2019 | 32038552 | Agriculture, Wheat, Climate change, Drought tolerance, PGPR, Phosphate Solubilization | | |
| Effects of Anchomanes difformis on Inflammation, Apoptosis, and Organ Toxicity in STZ-Induced Diabetic Cardiomyopathy. | Alabi TD, Chegou NN, Brooks NL, Oguntibeju OO. | Biomedicines | 10.3390/biomedicines8020029 | 2020 | 32046294 | Apoptosis, Oxidative stress, Inflammation, Diabetes, Cardiomyopathy, Glibenclamide, Anchomanes Difformis | Pathogenicity | |
| Chrysin Reduces Oxidative Stress but Does Not Affect Polyol Pathway in the Lenses of Type 1 Diabetic Rats. | Wojnar W, Zych M, Borymski S, Kaczmarczyk-Sedlak I. | Antioxidants (Basel) | 10.3390/antiox9020160 | 2020 | 32079112 | Rats, Oxidative stress, Oxidative damage, type 1 diabetes, lens, Chrysin | | |
| Heading Towards a Possible Rebirth of the Induced Renal Cell Carcinoma Models? | Mazzola CR, Ribatti D. | Cancers (Basel) | 10.3390/cancers12030598 | 2020 | 32150972 | Physiopathology, Kidney cancer, Renal Carcinogenesis, Key-words: Animal Models | | |
| Selective Modification of Streptozotocin at the C3 Position to Improve Its Bioactivity as Antibiotic and Reduce Its Cytotoxicity towards Insulin-Producing beta Cells. | Zhang J, Yakovlieva L, de Haan BJ, de Vos P, Minnaard AJ, Witte MD, Walvoort MTC. | Antibiotics (Basel) | 10.3390/antibiotics9040182 | 2020 | 32326389 | Antibiotics, Streptozotocin, Regioselective Oxidation | | |
| Dietary Fiber Protects against Diabetic Nephropathy through Short-Chain Fatty Acid-Mediated Activation of G Protein-Coupled Receptors GPR43 and GPR109A. | Li YJ, Chen X, Kwan TK, Loh YW, Singer J, Liu Y, Ma J, Tan J, Macia L, Mackay CR, Chadban SJ, Wu H. | J Am Soc Nephrol | 10.1681/asn.2019101029 | 2020 | 32358041 | Metabolism, Diabetic nephropathy, Chronic Inflammation, prevention & control, physiology, physiology, administration & dosage | Metabolism | Pathogenicity |
| Actinomycetes from the Red Sea Sponge Coscinoderma mathewsi: Isolation, Diversity, and Potential for Bioactive Compounds Discovery. | Shamikh YI, El Shamy AA, Gaber Y, Abdelmohsen UR, Madkour HA, Madkour HA, Horn H, Hassan HM, Elmaidomy AH, Alkhalifah DHM, Hozzein WN. | Microorganisms | 10.3390/microorganisms8050783 | 2020 | 32456212 | Micromonospora, Nocardia, Sponges, actinomycetes, Mycolic Acid, Cryptic, Gordonia, Lc-hresims | | |
| Animal Models of Diabetes-Associated Renal Injury. | Noshahr ZS, Salmani H, Khajavi Rad A, Sahebkar A. | J Diabetes Res | 10.1155/2020/9416419 | 2020 | 32566684 | Rodentia, pathology, Disease Models, Animal | | |
| Antihyperglycemic Potential of Back Tea Extract Attenuates Tricarboxylic Acid Cycle Enzymes by Modulating Carbohydrate Metabolic Enzymes in Streptozotocin-Induced Diabetic Rats. | Ramalingam S, Ramasamy SM, Vasu G, Gopalarishnan R. | Indian J Clin Biochem | 10.1007/s12291-019-00831-2 | 2020 | 32647410 | Diabetes, Tricarboxylic acid cycle, Streptozotocin, glucose metabolism, Black Tea | Metabolism | |
| Antidiabetic Potency, Antioxidant Effects, and Mode of Actions of Citrus reticulata Fruit Peel Hydroethanolic Extract, Hesperidin, and Quercetin in Nicotinamide/Streptozotocin-Induced Wistar Diabetic Rats. | Ali AM, Gabbar MA, Abdel-Twab SM, Fahmy EM, Ebaid H, Alhazza IM, Ahmed OM. | Oxid Med Cell Longev | 10.1155/2020/1730492 | 2020 | 32655759 | chemistry, drug therapy, therapeutic use, therapeutic use, therapeutic use, therapeutic use, metabolism | Metabolism | |
| Magnesium supplementation enhances insulin sensitivity and decreases insulin resistance in diabetic rats. | Liu H, Li N, Jin M, Miao X, Zhang X, Zhong W. | Iran J Basic Med Sci | 10.22038/ijbms.2020.40859.9650 | 2020 | 32952944 | Magnesium, Insulin receptor, Type 2 diabetes, Insulin sensitivity, Metabolic diseases | | |
| Topologically selective islet vulnerability and self-sustained downregulation of markers for beta-cell maturity in streptozotocin-induced diabetes. | Hahn M, van Krieken PP, Nord C, Alanentalo T, Morini F, Xiong Y, Eriksson M, Mayer J, Kostromina E, Ruas JL, Sharpe J, Pereira T, Berggren PO, Ilegems E, Ahlgren U. | Commun Biol | 10.1038/s42003-020-01243-2 | 2020 | 32999405 | pathology, pathology, pathology | | |
| Effects of a Nutritional Formulation Containing Caprylic and Capric Acid, Phosphatidylserine, and Docosahexaenoic Acid in Streptozotocin-Lesioned Rats. | Moura ELR, Dos Santos H, Celes APM, Bassani TB, Souza LC, Vital MABF. | J Alzheimers Dis Rep | 10.3233/adr-200175 | 2020 | 33163896 | Streptozotocin, Iba1, Object Recognition Test, Y Maze, Instanth® Neo | | |
| Streptomyces phaeolivaceus sp. nov. and Streptomyces broussonetiae sp. nov., isolated from the leaves and rhizosphere soil of Broussonetia papyrifera. | Mo P, Liu J, Zhao Y, Xu Z | Int J Syst Evol Microbiol | 10.1099/ijsem.0.004556 | 2020 | 33174827 | Bacterial Typing Techniques, Base Composition, Broussonetia/*microbiology, China, DNA, Bacterial/genetics, Fatty Acids/chemistry, Nucleic Acid Hybridization, *Phylogeny, Plant Leaves, RNA, Ribosomal, 16S/genetics, Rhizosphere, Sequence Analysis, DNA, *Soil Microbiology, Streptomyces/*classification/isolation & purification | Phylogeny | Transcriptome |
| Differences in the mechanism of type 1 and type 2 diabetes-induced skin dryness by using model mice. | Horikawa T, Hiramoto K, Goto K, Sekijima H, Ooi K. | Int J Med Sci | 10.7150/ijms.50764 | 2021 | 33390816 | Collagen, Hyaluronic acid, Diabetes, STZ, Skin Dryness, Kk-Ay/Tajcl Mice, pathology, etiology, complications, complications, complications | | |
| Antidiabetic effects of Maclura cochinchinensis (Lour.) corner heartwood extract. | Chewchinda S, Leakaya N, Sato H, Sato VH. | J Tradit Complement Med | 10.1016/j.jtcme.2019.10.004 | 2021 | 33511064 | Diabetic, Hypoglycemia, Stz, Streptozotocin, Oral Glucose Tolerance Test (Ogtt), Fbg, Fasting Blood Glucose, Ogtt, Oral Glucose Tolerance Test, Na, Nicotinamide, Cmc-na, Carboxymethylcellulose, Dnsa, 3, 5-Dinitrosalicylic Acid | | |
| Oral berberine improves brain dopa/dopamine levels to ameliorate Parkinson's disease by regulating gut microbiota. | Wang Y, Tong Q, Ma SR, Zhao ZX, Pan LB, Cong L, Han P, Peng R, Yu H, Lin Y, Gao TL, Shou JW, Li XY, Zhang XF, Zhang ZW, Fu J, Wen BY, Yu JB, Cao X, Jiang JD. | Signal Transduct Target Ther | 10.1038/s41392-020-00456-5 | 2021 | 33623004 | drug therapy, metabolism, pharmacology, drug effects | Metabolism | Pathogenicity |
| Intracerebral Injection of Streptozotocin to Model Alzheimer Disease in Rats. | Moreira-Silva D, Vizin RCL, Martins TMS, Ferreira TL, Almeida MC, Carrettiero DC. | Bio Protoc | 10.21769/bioprotoc.3397 | 2019 | 33654898 | Insulin, Memory, Glucose, Cognition, Tau, STZ, Protocol | | |
| Antihyperglycemic Activity of TLC Isolates from the Leaves of Aloe megalacantha Baker in Streptozotocin-Induced Diabetic Mice. | Araya TY, Karim A, Hailu GS, Periasamy G, Kahsay G. | Diabetes Metab Syndr Obes | 10.2147/dmso.s288313 | 2021 | 33758524 | Diabetes, Streptozotocin, thin layer chromatography, Antidiabetic, Aloe Megalacantha Baker | | |
| Chemotherapy in NEN: still has a role? | Espinosa-Olarte P, La Salvia A, Riesco-Martinez MC, Anton-Pascual B, Garcia-Carbonero R. | Rev Endocr Metab Disord | 10.1007/s11154-021-09638-0 | 2021 | 33843007 | Neuroendocrine Tumors, Intestinal Neoplasms, Stomach Neoplasms, Pancreatic Neoplasms | | |
| Contributions from Mexican Flora for the Treatment of Diabetes Mellitus: Molecules of Psacalium decompositum (A. Gray) H. Rob & Brettell. | Jimenez-Estrada M, Huerta-Reyes M, Tavera-Hernandez R, Alvarado-Sansininea JJ, Alvarez AB. | Molecules | 10.3390/molecules26102892 | 2021 | 34068304 | Diabetes mellitus, Antioxidant, Sesquiterpenes, Hypoglycemic, Anti-inflammatory, Mexican Medicinal Plants, Psacalium Decompositum, Cacalol, Cacalone, chemistry, therapy, chemistry | | |
| Vitamin D3 attenuates oxidative stress and regulates glucose level and leukocyte count in a semi-chronic streptozotocin-induced diabetes model. | Mitrasinovic-Brulic M, Dervisevic A, Zaciragic A, Focak M, Valjevac A, Hadzovic-Dzuvo A, Suljevic D. | J Diabetes Metab Disord | 10.1007/s40200-021-00814-2 | 2021 | 34178862 | Vitamin D, Malondialdehyde, Interleukin-17, Streptozotocin, eosinophilia, Monocytosis | | |
| Insights into the Endophytic Bacterial Microbiome of Crocus sativus: Functional Characterization Leads to Potential Agents that Enhance the Plant Growth, Productivity, and Key Metabolite Content. | Ahmad T, Farooq S, Mirza DN, Kumar A, Mir RA, Riyaz-Ul-Hassan S. | Microb Ecol | 10.1007/s00248-021-01810-y | 2022 | 34241654 | phytopathogens, Microbiome, Apocarotenoids, Acc Deaminase, Crocuses, Microbial Formulation, Crocus, Microbiota | | |
| A study on toxicity and anti-hyperglycemic effects of Abhrak Bhasma in rats. | Gopinath H, Shivashankar M. | J Ayurveda Integr Med | 10.1016/j.jaim.2021.03.004 | 2021 | 34362606 | Acute toxicity, Anti-diabetic, Sub-acute Toxicity, Abhrak Bhasma, Stz Induced | | |
| Onion (Allium cepa) and its Main Constituents as Antidotes or Protective Agents against Natural or Chemical Toxicities: A Comprehensive Review. | Dorrigiv M, Zareiyan A, Hosseinzadeh H. | Iran J Pharm Res | 10.22037/ijpr.2020.112773.13940 | 2021 | 34400937 | Toxicity, Allium cepa, Protective effect, Venom, Onion, Toxin, Antidote | | |
| Reclassification of four subspecies in the genus Streptomyces to Streptomyces rubradiris sp. nov., Streptomyces asoensis sp. nov., Streptomyces fructofermentans sp. nov. and Streptomyces ossamyceticus sp. nov. | Komaki H, Tamura T. | Int J Syst Evol Microbiol | 10.1099/ijsem.0.005078 | 2021 | 34787542 | Streptomyces, subspecies, reclassification, Streptomyces, Phylogeny | Phylogeny | |
| Antagonistic activity of endophytic actinobacteria from native potatoes (Solanum tuberosum subsp. tuberosum L.) against Pectobacterium carotovorum subsp. carotovorum and Pectobacterium atrosepticum. | Padilla-Galvez N, Luengo-Uribe P, Mancilla S, Maurin A, Torres C, Ruiz P, France A, Acuna I, Urrutia H. | BMC Microbiol | 10.1186/s12866-021-02393-x | 2021 | 34876006 | Potato, Streptomyces sp., Soft rot, Blackleg, Quorum Quenching, Confocal Laser Microscopy, Endophytic Actinobacteria, physiology, physiology, microbiology, physiology | | |
| Streptozotocin-Induced Diabetes in a Mouse Model (BALB/c) Is Not an Effective Model for Research on Transplantation Procedures in the Treatment of Type 1 Diabetes. | Wszola M, Klak M, Kosowska A, Tymicki G, Berman A, Adamiok-Ostrowska A, Olkowska-Truchanowicz J, Uhrynowska-Tyszkiewicz I, Kaminski A. | Biomedicines | 10.3390/biomedicines9121790 | 2021 | 34944607 | Glucose, Mouse, Animal model, Diabetic, Streptozotocin, C-peptide, T1d | | |
| Development, Characterization, Optimization, and In Vivo Evaluation of Methacrylic Acid-Ethyl Acrylate Copolymer Nanoparticles Loaded with Glibenclamide in Diabetic Rats for Oral Administration. | Guadarrama-Escobar OR, Sanchez-Vazquez I, Serrano-Castaneda P, Chamorro-Cevallos GA, Rodriguez-Cruz IM, Sanchez-Padron AY, Anguiano-Almazan E, Pena-Juarez MC, Mendez-Albores A, Dominguez-Delgado CL, Mercado-Marquez C, Rodriguez-Perez B, Escobar-Chavez JJ. | Pharmaceutics | 10.3390/pharmaceutics13122023 | 2021 | 34959305 | Diabetes mellitus, Glibenclamide, Glucose Control, Polymeric Nanoparticles, Polioxyl 40 Hydrogenated Castor Oil | | |
| Inhibition of phosphorylated calcium/calmodulin-dependent protein kinase IIalpha relieves streptozotocin-induced diabetic neuropathic pain through regulation of P2X3 receptor in dorsal root ganglia. | He XF, Kang YR, Fei XY, Chen LH, Li X, Ma YQ, Hu QQ, Qu SY, Wang HZ, Shao XM, Liu BY, Yi-Liang, Du JY, Fang JQ, Jiang YL. | Purinergic Signal | 10.1007/s11302-021-09829-z | 2023 | 34973115 | DRG, Streptozotocin, Diabetic Neuropathic Pain, P2x3 Receptor, Kn93, Neuralgia, Diabetic Neuropathies, Diabetes Mellitus, Experimental | | |
| Genome Sequence-Guided Finding of Lucensomycin Production by Streptomyces achromogenes Subsp. streptozoticus NBRC14001. | Nishimura S, Nakamura K, Yamamoto M, Morita D, Kuroda T, Kumagai T. | Microorganisms | 10.3390/microorganisms10010037 | 2021 | 35056487 | Streptomyces, Antifungal compound, Polyene Macrolide, Genome-guided Approach, Lucensomycin | Genetics | |
| Pathogenic Mechanism of Autoimmune Diabetes Mellitus in Humans: Potential Role of Streptozotocin-Induced Selective Autoimmunity against Human Islet beta-Cells. | Zhu BT. | Cells | 10.3390/cells11030492 | 2022 | 35159301 | Pathogenic mechanism, Autoimmune Diabetes, Islets of Langerhans, Diabetes Mellitus, Experimental, Diabetes Mellitus, Type 1 | | |
| Amycolatopsis camponoti sp. nov., new tetracenomycin-producing actinomycete isolated from carpenter ant Camponotus vagus. | Zakalyukina YV, Osterman IA, Wolf J, Neumann-Schaal M, Nouioui I, Biryukov MV. | Antonie Van Leeuwenhoek | 10.1007/s10482-022-01716-w | 2022 | 35218449 | Actinobacteria, Tetracenomycin X, Amycolatopsis Camponoti Sp. Nov., Amycolatpsis Sp, Camponotus Vagus, Ants, Actinobacteria | | |
| Aloe vera and Streptozotocin-Induced Diabetes Mellitus. | Haghani F, Arabnezhad MR, Mohammadi S, Ghaffarian-Bahraman A. | Rev Bras Farmacogn | 10.1007/s43450-022-00231-3 | 2022 | 35287334 | Biochemical parameters, Biological properties, Pathophysiology, Side effects, Phytocomponents | | |
| Phase I/II study of streptozocin monotherapy in Japanese patients with unresectable or metastatic gastroenteropancreatic neuroendocrine tumors. | Komoto I, Kokudo N, Aoki T, Morizane C, Ito T, Hashimoto T, Kimura W, Inoue N, Hasegawa K, Kondo S, Ueno H, Igarashi H, Oono T, Makuuchi M, Takamoto T, Hirai I, Takeshita A, Imamura M. | Jpn J Clin Oncol | 10.1093/jjco/hyac048 | 2022 | 35411926 | Disease control, streptozocin, Neuroendocrine Tumor, Tumor Shrinkage, Neuroendocrine Tumors | | |
| New Advances on Pathophysiology of Diabetes Neuropathy and Pain Management: Potential Role of Melatonin and DPP-4 Inhibitors. | Busa P, Kuthati Y, Huang N, Wong CS. | Front Pharmacol | 10.3389/fphar.2022.864088 | 2022 | 35496279 | Melatonin, Antioxidant, Diabetes Mellitus (DM), Neuropathic pain, Anti-inflammatory, neuroinflammation, Redox Levels | Pathogenicity | |
| Therapeutic Effect of P-Cymene on Lipid Profile, Liver Enzyme, and Akt/Mtor Pathway in Streptozotocin-Induced Diabetes Mellitus in Wistar Rats. | Arabloei Sani M, Yaghmaei P, Hajebrahimi Z, Hayati Roodbari N. | J Obes | 10.1155/2022/1015669 | 2022 | 35528246 | Diabetes Mellitus, Experimental, Metformin, Cymenes | | |
| Deconvoluting the dual hypoglycemic effect of wedelolactone isolated from Wedelia calendulacea: investigation via experimental validation and molecular docking. | Kumar V, Sharma K, Ahmed B, Al-Abbasi FA, Anwar F, Verma A, Verma A. | RSC Adv | 10.1039/c7ra12568b | 2018 | 35542112 | | | |
| Myrtenal mitigates streptozotocin-induced spatial memory deficit via improving oxido inflammatory, cholinergic and neurotransmitter functions in mice. | Akefe IO, Adegoke VA, Lamidi IY, Ameh MP, Idoga ES, Ubah SA, Ajayi IE. | Curr Res Pharmacol Drug Discov | 10.1016/j.crphar.2022.100106 | 2022 | 35570857 | Mice, Memory, Antioxidant, Streptozotocin, Dementia, Myrtenal | | |
| Comprehensive genome analysis of Lentzea reveals repertoire of polymer-degrading enzymes and bioactive compounds with clinical relevance. | Maiti PK, Mandal S. | Sci Rep | 10.1038/s41598-022-12427-7 | 2022 | 35589875 | Actinomycetales, Anti-Infective Agents | | |
| Effects of alcoholic extract of Terminalia Chebula dried fruit on blood biochemical profile in diabetic rats. | Eltimamy M, Elshamarka M, Aboelsaad M, Sayed M, Moawad H. | J Diabetes Metab Disord | 10.1007/s40200-021-00951-8 | 2022 | 35673508 | Streptozotocin, T2DM, Terminalia Chebula | | |
| Micronized Dietary Okara Fiber: Characterization, Antioxidant, Antihyperglycemic, Antihyperlipidemic, and Pancreato-Protective Effects in High Fat Diet/Streptozotocin-Induced Diabetes Mellitus. | Huang Y, Ashaolu TJ, Olatunji OJ. | ACS Omega | 10.1021/acsomega.2c01541 | 2022 | 35722005 | | | |
| Maternal diabetes negatively impacts fetal health. | Gonzalez Corona C, Parchem RJ. | Open Biol | 10.1098/rsob.220135 | 2022 | 36128718 | Pancreas, Insulin, Diabetes, Birth defects, Hyperglycaemia, Diabetes, Gestational | | |
| Silymarin reduces retinal microvascular damage in streptozotocin-induced diabetic rats. | Karimi R, Bakhshi A, Dayati P, Abazari O, Shahidi M, Savaee M, Kafi E, Rahmanian M, Naghib SM. | Sci Rep | 10.1038/s41598-022-20297-2 | 2022 | 36151457 | Diabetic Retinopathy, Diabetes Mellitus, Experimental, Silymarin | | |
| Kribbellichelins A and B, Two New Antibiotics from Kribbella sp. CA-293567 with Activity against Several Human Pathogens. | Virues-Segovia JR, Reyes F, Ruiz S, Martin J, Fernandez-Pastor I, Justicia C, de la Cruz M, Diaz C, Mackenzie TA, Genilloud O, Gonzalez I, Tormo JR. | Molecules | 10.3390/molecules27196355 | 2022 | 36234892 | Cytotoxic activity, Antifungal activity, Actinobacteria, Antibacterial activity, Structural elucidation, antibiotic activity, Kribbella, Actinomycetales, Anti-Infective Agents | | |
| Intestinal Region-Dependent Alterations of Toll-Like Receptor 4 Expression in Myenteric Neurons of Type 1 Diabetic Rats. | Bodi N, Egyed-Kolumban A, Onhausz B, Barta BP, Doghmi AA, Balazs J, Szalai Z, Bagyanszki M. | Biomedicines | 10.3390/biomedicines11010129 | 2023 | 36672637 | Insulin, Toll-like receptor 4, Enteric nervous system, type 1 diabetes, Toll-like receptors, hyperglycemia, Myenteric Neurons, Gut-region Specificity | Pathogenicity | |
| Effects of diabetes on microglial physiology: a systematic review of in vitro, preclinical and clinical studies. | Vargas-Soria M, Garcia-Alloza M, Corraliza-Gomez M. | J Neuroinflammation | 10.1186/s12974-023-02740-x | 2023 | 36869375 | Retina, Brain, Diabetes mellitus, Cytokines, Oxidative stress, Microglia, hyperglycemia, neuroinflammation, Dementia, Diabetes Mellitus, Hyperglycemia | Pathogenicity | |
| YQBS Improves Cognitive Dysfunction in Diabetic Rats: Possible Association with Tyrosine and Tryptophan Metabolism. | Liu Y, Cai J, Wang Y, Zhao X, Qiao Y, Liu CJ. | Diabetes Metab Syndr Obes | 10.2147/dmso.s401863 | 2023 | 37021127 | Diabetes mellitus, Hippocampus, Metabolomics, Cognitive Dysfunction, Yi-qi-bu-shen | | |
| Antidotal and protective effects of mangosteen (Garcinia mangostana) against natural and chemical toxicities: A review. | Mohammadi Zonouz A, Ghasemzadeh Rahbardar M, Hosseinzadeh H. | Iran J Basic Med Sci | 10.22038/ijbms.2023.66900.14674 | 2023 | 37051107 | Apoptosis, Analgesics, Anti-inflammatory agents, hypoglycemic agents, neuroprotective agents, xanthones, Phytotherapy, Anti-oxidants | | |
| Analysis of Antidiabetic Activity of Squalene via In Silico and In Vivo Assay. | Widyawati T, Syahputra RA, Syarifah S, Sumantri IB. | Molecules | 10.3390/molecules28093783 | 2023 | 37175192 | In vivo, Diabetic mellitus, Squalene, In silico, Diabetes Mellitus, Type 2, Metformin | | |
| The Beneficial Effect of Swimming Training Associated with Quercetin Administration on the Endothelial Nitric Oxide-Dependent Relaxation in the Aorta of Rats with Experimentally Induced Type 1 Diabetes Mellitus. | Chis IC, Micu CM, Toader A, Moldovan R, Lele L, Clichici S, Mitrea DR. | Metabolites | 10.3390/metabo13050586 | 2023 | 37233627 | Endothelium, Acetylcholine, Quercetin, Diabetes, Aorta, Moderate Swimming Training | | |
| Intermittent theta burst stimulation attenuates oxidative stress and reactive astrogliosis in the streptozotocin-induced model of Alzheimer's disease-like pathology. | Stanojevic JB, Zeljkovic M, Dragic M, Stojanovic IR, Ilic TV, Stevanovic ID, Ninkovic MB. | Front Aging Neurosci | 10.3389/fnagi.2023.1161678 | 2023 | 37273654 | Oxidative stress, Astrocytes, Streptozotocin, Itbs | | |
| Experimental Models to Study Diabetes Mellitus and Its Complications: Limitations and New Opportunities. | Martin-Carro B, Donate-Correa J, Fernandez-Villabrille S, Martin-Virgala J, Panizo S, Carrillo-Lopez N, Martinez-Arias L, Navarro-Gonzalez JF, Naves-Diaz M, Fernandez-Martin JL, Alonso-Montes C, Cannata-Andia JB. | Int J Mol Sci | 10.3390/ijms241210309 | 2023 | 37373455 | Diabetes mellitus, Diabetic Kidney Disease, Experimental Diabetic Models, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2 | | |
| A review of the biological effects of Myrtus communis. | Dabbaghi MM, Fadaei MS, Soleimani Roudi H, Baradaran Rahimi V, Askari VR. | Physiol Rep | 10.14814/phy2.15770 | 2023 | 37464095 | Antioxidant, Toxin, Anti-inflammatory, Myrtle, Myrtus Communis, Myrtus, Anti-Infective Agents | | |
| Unveiling the Pharmacological Significance of Marine Streptomyces violaceusniger KS20: Isolation, Characterization, and Assessment of Its Biomedical Applications. | Chakraborty B, Shashiraj KN, Kumar RS, Bhat MP, Basavarajappa DS, Almansour AI, Perumal K, Nayaka S. | Metabolites | 10.3390/metabo13091022 | 2023 | 37755302 | GC-MS analysis, A549 cell line, Antiproliferative Activity, Pc-3 Cell Line, Streptomyces Violaceusniger, Antimycobacterial Efficacy | | |
| Role of the Microbiota in Skin Neoplasms: New Therapeutic Horizons. | Savoia P, Azzimonti B, Rolla R, Zavattaro E. | Microorganisms | 10.3390/microorganisms11102386 | 2023 | 37894044 | Melanoma, Microbiota, Skin Cancer, Cutaneous Carcinogenesis | | |
| Protective effect of eriodictyol against hyperglycemia-induced diabetic nephropathy in rats entails antioxidant and anti-inflammatory effects mediated by activating Nrf2. | AlTamimi JZ, AlFaris NA, Alshammari GM, Alagal RI, Aljabryn DH, Abdo Yahya M. | Saudi Pharm J | 10.1016/j.jsps.2023.101817 | 2023 | 37915829 | Kidney, Antioxidant, Diabetes, Anti-inflammatory, Streptozotocine, Eriodictyol | | |
| Green synthesis of silver nanoparticles from plant Fagonia cretica and evaluating its anti-diabetic activity through indepth in-vitro and in-vivo analysis. | Khan HA, Ghufran M, Shams S, Jamal A, Khan A, Abdullah, Awan ZA, Khan MI. | Front Pharmacol | 10.3389/fphar.2023.1194809 | 2023 | 37936909 | Oxidative stress, Diabetes, STZ, Agnps, Biogenic Nanoparticles, F. Cretica | | |
| Okra [Abelmoschus esculentus (L.) Moench] improved blood glucose and restored histopathological alterations in splenic tissues in a rat model with streptozotocin-induced type 1 diabetes through CD8+ T cells and NF-kbeta expression. | Alblihd MA, Alsharif KF, Hamad AA, Ali FAZ, Hussein MT, Alhegaili AS, Hassan MA, Al-Amer OM, Albezrah NKA, Almalki AA, Albarakati AJA, Alghamdi KS, Alzahrani KJ, Albrakati A, Alrubai EH, ElAshmouny N, Elmahallawy EK. | Front Vet Sci | 10.3389/fvets.2023.1268968 | 2023 | 38046568 | Lymphocyte, Diabetes, White pulp, Hemosiderosis, Okra | | |
| Predictive Factors of Response to Streptozotocin in Neuroendocrine Pancreatic Neoplasms. | Fanciulli G, La Salvia A, Di Molfetta S, Cannavale G, Puliani G, Verrico M, Campolo F, Colao A, Faggiano A, Nike Group. | J Clin Med | 10.3390/jcm12247557 | 2023 | 38137624 | Streptozotocin, Predictors Of Response, Neuroendocrine Pancreatic Neoplasm | | |
| Chitosan Versus Dapagliflozin in a Diabetic Cardiomyopathy Mouse Model. | Tartea G, Popa-Wagner A, Sfredel V, Mitran SI, Dan AO, Tuca AM, Preda AN, Raicea V, Tieranu E, Cozma D, Vatasescu R. | Int J Mol Sci | 10.3390/ijms25042118 | 2024 | 38396795 | Diabetes mellitus, Chitosan, Cardiomyopathy, Dapagliflozin, Diabetes Mellitus, Type 1, Benzhydryl Compounds, Chitosan, Glucosides, Diabetic Cardiomyopathies | | |
| Lin28 affects the proliferation and osteogenic differentiation of human dental pulp stem cells by directly inhibiting let-7b maturation. | Yan L, Sun J, Wang Y, Liu X, Liu X, Hu J, Sun M, Suo X, Duan R, Yuan C. | BDJ Open | 10.1038/s41405-024-00194-8 | 2024 | 38443392 | | | |
| Potential anti-hyperglycemic activity of black tea theaflavins through inhibiting alpha-amylase. | Li M, Dong Y, Kang M, Tao T, Li W, Zhang S, Quan W, Liu Z. | Food Chem X | 10.1016/j.fochx.2024.101296 | 2024 | 38550892 | Interaction mechanism, Theaflavins, Hypoglycemic activity, Black Tea | | |
| Comparative Screening of the Liver Gene Expression Profiles from Type 1 and Type 2 Diabetes Rat Models. | Guerra-Avila PL, Guzman TJ, Vargas-Guerrero B, Dominguez-Rosales JA, Cervantes-Garduno AB, Salazar-Montes AM, Sanchez-Orozco LV, Gurrola-Diaz CM. | Int J Mol Sci | 10.3390/ijms25084151 | 2024 | 38673735 | Wistar rats, Streptozotocin (STZ), Insulin resistance (IR), Type 1 Diabetes (T1d), Type 2 Diabetes (T2d), High-fat Diet (Hfd), Liver, Diabetes Mellitus, Experimental, Diabetes Mellitus, Type 2 | | |
| pH responsive fabrication of PVA-stabilized selenium nano formulation encapsulated with luteolin to reduce diabetic ureteral injury by decreasing NLRP3 inflammasome via Nrf2/ARE signaling. | Jing Q, Liu F, Yao W, Zhang X. | Regen Ther | 10.1016/j.reth.2024.04.009 | 2024 | 38699396 | Luteolin, Streptozotocin, ureteral injury, Diabetics, Lt-senps | | |
| Linalool exerts antioxidant activity in a rat model of diabetes by increasing catalase activity without antihyperglycemic effect. | Bar S, Kara M. | Exp Ther Med | 10.3892/etm.2024.12648 | 2024 | 39071903 | Catalase, Antioxidants, Diabetes mellitus, Linalool | | |
| Impact of streptozotocin-induced diabetes on experimental masseter pain in rats. | Costa YM, Herculiani CCF, Soares FFC, Azevedo MCS, Conti PCR, Dionisio TJ, Oliveira GM, Faria FAC, Santos CF, Garlet GP, Bonjardim LR. | Braz Oral Res | 10.1590/1807-3107bor-2024.vol38.0073 | 2024 | 39109769 | Masseter Muscle, Rats, Wistar, Diabetes Mellitus, Experimental, Streptozocin, Cytokines | | |
| Preclinical Evaluation of Sigma 1 Receptor Antagonists as a Novel Treatment for Painful Diabetic Neuropathy. | Peng Y, Zhang AH, Wei L, Welsh WJ. | ACS Pharmacol Transl Sci | 10.1021/acsptsci.4c00186 | 2024 | 39144554 | | | |
| Empagliflozin alone and in combination with metformin mitigates diabetes-associated renal complications. | Madhag Z, Al-Isawi Z. | J Med Life | 10.25122/jml-2023-0301 | 2024 | 39144694 | Apoptosis, Inflammation, Diabetes, Nephropathy, Metformin, Empagliflozin, Rats, Sprague-Dawley, Diabetic Nephropathies, Diabetes Mellitus, Experimental, Metformin, Benzhydryl Compounds, Glucosides | Pathogenicity | |
| Therapeutic Potential of Rosa davurica Pall. Root Extract as an Antidiabetic Agent: A Comprehensive Analysis from Molecular Mechanisms to In Vivo Efficacy. | Hwang DH, Asirvatham RD, Mohan Prakash RL, Kang C, Kim E. | Int J Mol Sci | 10.3390/ijms25168944 | 2024 | 39201631 | Antioxidant, STZ, PI3K, diabetic rat, Ampk, Rosa Davurica Pall., Rosa, Plant Roots, Diabetes Mellitus, Experimental, Plant Extracts, Hypoglycemic Agents, Glucose Transporter Type 4 | | |
| Enhanced Insulin Secretion Through Upregulation of Transcription Factors by Hydroalcoholic Extract of Securigera securidaca Seeds in Diabetic Animal Model. | Hasani M, Abbasi-Oshaghi E, Khomari F, Kiani B, Mirzaei F, Alipourfard I, Khodadadi I, Tayebinia H, Babaei M, Alizadeh-Fanalou S, Bahreini E. | Endocrinol Diabetes Metab | 10.1002/edm2.515 | 2024 | 39238175 | Insulin, Diabetes, NRF2, Pdx1, Fgf21, Mafa, Securigera Securidaca, Seeds, Diabetes Mellitus, Experimental, Insulin, Plant Extracts, Up-Regulation, Insulin Secretion | | |
| Dual-Action Therapeutics: DNA Alkylation and Antimicrobial Peptides for Cancer Therapy. | Andres CMC, Perez de la Lastra JM, Munguira EB, Andres Juan C, Perez-Lebena E. | Cancers (Basel) | 10.3390/cancers16183123 | 2024 | 39335095 | Cancer, Chemotherapy, Alkylating agents, Dna Alkylation, Dna Damage And Mutations | | |
| Longitudinal Analysis of Bone Metabolic Markers and Bone Mechanical Properties in STZ-Induced Diabetic Rats. | Tomaszewska E, Dobrowolski P, Muszynski S, Donaldson J, Golynski M, Zwolska J, Szadkowski M, Oseka M, Mielnik-Blaszczak M, Balicki I. | J Clin Med | 10.3390/jcm13185595 | 2024 | 39337082 | Diabetes mellitus, Rat, Bone, Streptozotocin | | |
| Neuroprotective Effects of Bexarotene and Icariin in a Diabetic Rat Model. | Agircan D, Parlak TM, Tufan O, Demircioglu M, Dik B. | Cureus | 10.7759/cureus.68238 | 2024 | 39347352 | Neurodegenerative diseases, Icariin, neuroprotective agents, Bexarotene, Type 2 Diabetes Mellitus (Type 2 Dm) | | |
| Neuroprotective effect of Lannea egregia Alkaloid-rich leaf extracts in streptozotocin-induced diabetic rats. | Ajiboye BO, Ekundayo BE, Salami AW, Osukoya AO, Komolafe K, Gaur S, Oyinloye BE, Jeje TO, Ojo OA. | Toxicol Rep | 10.1016/j.toxrep.2024.101742 | 2024 | 39376468 | Neurotransmitters, Oxidative stress, Alkaloid, Cholinesterase, Lannea Egregia | | |
| Mechanism of streptozotocin to induce cardiac fibrosis through TNFa and Bcl2 pathways in in silico and in vivo study. | Fatimah N, Mustika A, Mustika A, Sudjarwo SA. | Open Vet J | 10.5455/ovj.2024.v14.i9.17 | 2024 | 39553747 | In vivo, Diabetes, Streptozotocin, Cardiovascular risk factors, In silico, Rats, Wistar, Diabetes Mellitus, Experimental, Fibrosis, Streptozocin, Tumor Necrosis Factor-alpha, Proto-Oncogene Proteins c-bcl-2 | | |
| Complete Genome Assembly of Amycolatopsis bartoniae DSM 45807T Allows the Characterization of a Novel Glycopeptide Biosynthetic Gene Cluster. | Stepanyshyn A, Ruckert-Reed C, Busche T, Yaruta B, Andreo-Vidal A, Marinelli F, Kalinowski J, Yushchuk O. | Genes (Basel) | 10.3390/genes15121651 | 2024 | 39766918 | Genome sequencing, actinomycetes, Biosynthetic gene cluster, In Silico Analysis, Glycopeptide Antibiotics, Glycopeptides, Genome, Bacterial, Multigene Family, Amycolatopsis | Genetics | |
| Evaluation of the antihyperglycemic and antihyperlipidemic effects of Trigonella foenum-graecum L and Coffea arabica L seeds in STZ induced diabetic mice: impact on kidney and liver functions. | Muluye D, Getachew P, Tekalign T, Woldekidan S, Biftu T. | Pan Afr Med J | 10.11604/pamj.2024.49.94.44735 | 2024 | 40060282 | Diabetes mellitus, Hyperlipidemia, Streptozotocin, hyperglycemia, Chlorogenic Acid-treated, Galactomannan-treated, Trigonella, Coffea, Diabetes Mellitus, Experimental, Plant Extracts, Hypoglycemic Agents, Hypolipidemic Agents | | |
| Isolation, characterization and screening of phosphate (P) solubilizing actinomycetes and exploring its potency in finger millet (Eleusine coracana L.). | Babu PM, Panda N, Nayak RK, Sethi D, Biswal S, Mishra MK, Datta S, Karubakee S, Suchitha NS, Prusty M, Nayak A, Dash R, Pattanayak SK. | BMC Plant Biol | 10.1186/s12870-025-06385-1 | 2025 | 40114072 | Isolation, Phosphorus, Solubilization, Genomics, biochemical, Finger Millet, Actinobacteria, Eleusine, Phosphates, Soil Microbiology | Phylogeny | Genetics |
| The mechanism underlying streptozotocin injection for the development of a nontransgenic Alzheimer's disease animal model. | Titisari N, Ahmad H, Samsulrizal N, Fauzi A, Abdul Razak IS. | Open Vet J | 10.5455/ovj.2025.v15.i2.8 | 2025 | 40201829 | Brain, Neuron, tau Protein, beta-amyloid, hyperglycemia, Alzheimer Disease, Diabetes Mellitus, Experimental, Disease Models, Animal, Streptozocin | | |
| Limettin and PD98059 Mitigated Alzheimer's Disease Like Pathology Induced by Streptozotocin in Mouse Model: Role of p-ERK1/2/p-GSK-3beta/p-CREB/BDNF Pathway. | Hassan RM, Elsayed NS, Assaf N, Budzynska B, Skalicka-Wozniak K, Ibrahim SM. | J Neuroimmune Pharmacol | 10.1007/s11481-025-10211-8 | 2025 | 40381124 | STZ, PD98059, neuroinflammation, P-erk1/2, Limettin, Alzheimer Disease, Flavonoids, MAP Kinase Signaling System | Pathogenicity | |
| Therapeutic Potential of Lythrum salicaria L. Ethanol Extract in Experimental Rat Models of Streptozotocin-Induced Diabetes Mellitus and Letrozole-Induced Polycystic Ovary Syndrome. | Usatiuc LO, Parvu M, Pop RM, Uifalean A, Valean D, Surd A, Ticolea M, Hiruta A, Ranga F, Catoi FA, Catana C, Parvu AE. | Antioxidants (Basel) | 10.3390/antiox14050573 | 2025 | 40427455 | Diabetes mellitus, Oxidative stress, Inflammation, Insulin resistance, Polycystic ovary syndrome, Lythrum Salicaria L. | Pathogenicity | |
| Multitargeted Effects of Plantago ovata Ethanol Extract in Experimental Rat Streptozotocin-Induced Diabetes Mellitus and Letrozole-Induced Polycystic Ovary Syndrome. | Usatiuc LO, Pop RM, Adrian S, Parvu M, Ticolea M, Uifalean A, Valean D, Gavrilas LI, Csilla-Eniko S, Leopold LF, Ranga F, Catoi FA, Parvu AE. | Int J Mol Sci | 10.3390/ijms26104712 | 2025 | 40429855 | Diabetes mellitus, Oxidative stress, Inflammation, Polycystic ovary syndrome, Plantago Ovata, Polycystic Ovary Syndrome, Diabetes Mellitus, Experimental, Plant Extracts | Pathogenicity | |
| Blunted pressor response to peripheral sensory afferent nerve stimulation in intracerebroventricular-streptozotocin injected rats. | Fukazawa A, Hotta N, Yeganehjoo H, Hori A, Kim HK, Iwamoto GA, Smith SA, Vongpatanasin W, Mizuno M. | Auton Neurosci | 10.1016/j.autneu.2025.103315 | 2025 | 40561701 | Streptozotocin, Mechanoreflex, Sporadic Alzheimer's Disease, And Metaboreflex, Peripheral Nerves, Streptozocin, Blood Pressure | | |
| Ethyl acetate extract of Knoxia roxburghii (Rubiaceae) down-regulates ECHDC1, CAMK2D, DDB1, UBA6, BIRC6, and HK1 proteins and ameliorates the symptoms of diabetes mellitus. | Wang X, Tian X, Xu Y, Li R, Qumo G, Li J, Bao N, Li M, Qiu B. | Front Pharmacol | 10.3389/fphar.2025.1587858 | 2025 | 40766763 | Oxidative, Proteomics, Diabetes, Metabolomics, Prm, Herb Extract | | |
| Efficacy of Streptomyces achromogenes MAA01-influenced hydroxyapatite/graphene oxide nanocomposites for bone ossification. | Kandiah K, Negara W, Arumugam P, Subramaniam RT, Handayani M, Kamaraj C. | 3 Biotech | 10.1007/s13205-025-04444-w | 2025 | 40809190 | Actinobacteria, Wistar rat, Graphene Oxide, Bone Ossification, Hap Nanocomposites | | |
| Upscaling, toxicity and efficacy of multifaceted dressing embedded with dsirna-loaded gold nanoparticles for enhancing diabetic wound treatment. | Faris Taufeq FY, Nordin ML, Katas H. | PLoS One | 10.1371/journal.pone.0327375 | 2025 | 40911569 | Diabetes Mellitus, Experimental, Gold, Bandages, Wound Healing, Metal Nanoparticles | | |
| Comparative effects of streptozotocin, dehydroepiandrosterone and letrozole with high fat diet on ovarian injury induction and functional impairment. | Yu L, Peng Q, Ma C, Ouyang J, Ma H, Fan S, Sun M, Ma H, Du X, Zhu X, Li G, He R. | Sci Rep | 10.1038/s41598-025-20174-8 | 2025 | 41062642 | Environment, DHEA, letrozole, Streptozotocin, Ovarian function, Ovary, Streptozocin, Dehydroepiandrosterone, Diet, High-Fat, Letrozole | | |
| Structural insights into heme-iron dependent N-N bond formation enzyme LnzB. | Huang H, Wang L, Chen P, Yang T, Zhu C, Li S, Zhou Y, Tan Y, Li Z, Zhang H, Chen J, Zhang ZM. | Commun Chem | 10.1038/s42004-025-01724-7 | 2025 | 41214184 | | | |
| Evaluation of Rat Testicular Cell Populations in Experimental Condition of Diabetes Induced in Early Postnatal Life. | Pavlova E, Ivanov R, Abadjieva D, Gluhcheva Y, Petrova E, Vladov I, Lakova E, Atanassova N. | Cells | 10.3390/cells14211714 | 2025 | 41227359 | Germ cells, Testis, Diabetes mellitus, Sertoli cells, Leydig cells, Testis, Diabetes Mellitus, Experimental | | |
| Streptozotocin Causes Blood-Brain Barrier and Astrocytic Dysfunction In Vitro. | Habib SA, Kamal MM, Aly MH, Ghaiad HR, Rizk SM, Banks WA, Erickson MA. | Cells | 10.3390/cells14211745 | 2025 | 41227390 | Astrocytes, Streptozotocin, Tight junctions, Glut-1, Brain Endothelial Cells, Blood-Brain Barrier, Astrocytes, Streptozocin | | |
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