Cite the latest
BacDive paper
×

Rate our new design

Thank you!
BacDive D3
Content
Advanced search Isolation sources API ® test finder TAXplorer Statistics Special collections Download selection Web services SPARQL
About us
About Team Contact Tutorials News Mailinglist
BacDive ID 15113
Type strain
Culture col. no. DSM 40147 ATCC 19744 ATCC 19897 CBS 483.68 ETH 24195 IFO 12760 INA 815/54 ISP 5147 NBRC 12760 RIA 1025 JCM 4362 BCRC 11466 CBS 111.60 CGMCC 4.1625 IMET 43743 NCIMB 10030 NCIMB 9596 NRRL 3241 NRRL B-2583 VKM Ac-1844 15 more
NCBI tax ID(s) 66881
Links
For citation purpose refer to the digital object identifier (doi) of the current version.

Archive

version 10 (current version):
version 10 (current version)

General

@ref: 9347

BacDive-ID: 15113

DSM-Number: 40147

keywords: genome sequence, 16S sequence, mesophilic, antibiotic compound production

description: Streptomyces cremeus DSM 40147 is a mesophilic prokaryote that produces antibiotic compounds and was isolated from soil.

NCBI tax id

  • NCBI tax id: 66881
  • Matching level: species

strain history

@refhistory
9347<- E.B. Shirling, ISP <- T.P. Preobrazhenskaya, INA
67770KCC S-0362 <-- IFO 12760 <-- SAJ <-- ISP 5147 <-- INA 815/54.

doi: 10.13145/bacdive15113.20251217.10

Name and taxonomic classification

LPSN

  • @ref: 20215
  • description: kingdom/bacillati
  • keyword: phylum/actinomycetota
  • phylum: Actinomycetota
  • class: Actinomycetes
  • order: Kitasatosporales
  • family: Streptomycetaceae
  • genus: Streptomyces
  • species: Streptomyces cremeus
  • full scientific name: Streptomyces cremeus (Kudrina 1957) Pridham et al. 1958 (Approved Lists 1980)

  • synonyms

    • @ref: 20215
    • synonym: Actinomyces cremeus

@ref: 9347

domain: Bacteria

phylum: Actinobacteria

class: Actinobacteria

order: Actinomycetales

family: Streptomycetaceae

genus: Streptomyces

species: Streptomyces cremeus

full scientific name: Streptomyces cremeus (Kudrina 1957) Pridham et al. 1958

type strain: yes

Culture and growth conditions

culture medium

  • @ref: 9347
  • name: GYM STREPTOMYCES MEDIUM (DSMZ Medium 65)
  • growth: yes
  • link: https://mediadive.dsmz.de/medium/65
  • composition: Name: GYM STREPTOMYCES MEDIUM (DSMZ Medium 65) Composition: Agar 18.0 g/l Malt extract 10.0 g/l Yeast extract 4.0 g/l Glucose 4.0 g/l CaCO3 2.0 g/l Distilled water

culture temp

@refgrowthtypetemperature
18546positiveoptimum28
9347positivegrowth28
67770positivegrowth28

Physiology and metabolism

compound production

@refcompound
9347cremomycin
20216Cremomycin

metabolite utilization

@refChebi-IDmetaboliteutilization activitykind of utilization tested
1854617234glucose+
1854622599arabinose+
1854617992sucrose-
1854618222xylose-
1854617268myo-inositol-
1854629864mannitol-
1854628757fructose-
1854626546rhamnose-
1854616634raffinose-
1854662968cellulose+
683685291gelatin+hydrolysis
6836827897tryptophan-energy source
6836816199urea+hydrolysis
6836816947citrate+assimilation
6836818257ornithine-degradation
6836825094lysine-degradation
6836829016arginine-hydrolysis

metabolite production

@refChebi-IDmetaboliteproduction
6836815688acetoinyes
6836835581indoleno
6836816136hydrogen sulfideyes

metabolite tests

@refChebi-IDmetabolitevoges-proskauer-testindole test
6836815688acetoin+
6836835581indole-

enzymes

@refvalueactivityec
68382alkaline phosphatase+3.1.3.1
68382esterase (C 4)+
68382esterase lipase (C 8)+
68382lipase (C 14)-
68382leucine arylamidase+3.4.11.1
68382valine arylamidase+
68382cystine arylamidase+3.4.11.3
68382trypsin+3.4.21.4
68382alpha-chymotrypsin+3.4.21.1
68382acid phosphatase+3.1.3.2
68382naphthol-AS-BI-phosphohydrolase+
68382alpha-galactosidase-3.2.1.22
68382beta-galactosidase+3.2.1.23
68382beta-glucuronidase-3.2.1.31
68382alpha-glucosidase+3.2.1.20
68382beta-glucosidase+3.2.1.21
68382N-acetyl-beta-glucosaminidase+3.2.1.52
68382alpha-mannosidase+3.2.1.24
68382alpha-fucosidase-3.2.1.51
68368ornithine decarboxylase-4.1.1.17
68368gelatinase+
68368tryptophan deaminase-4.1.99.1
68368urease+3.5.1.5
68368lysine decarboxylase-4.1.1.18
68368arginine dihydrolase-3.5.3.6
68368beta-galactosidase-3.2.1.23

API zym

@refAlkaline phosphataseEsteraseEsterase LipaseLipaseLeucine arylamidaseValine arylamidaseCystine arylamidaseTrypsinalpha- ChymotrypsinAcid phosphataseNaphthol-AS-BI-phosphohydrolasealpha- Galactosidasebeta- Galactosidasebeta- Glucuronidasealpha- Glucosidasebeta- GlucosidaseN-acetyl-beta- glucosaminidasealpha- Mannosidasealpha- Fucosidase
18546+++-+++++++-+-++++-

API 20E

@refONPGADH ArgLDC LysODCCITH2SURETDA TrpINDVPGEL
18546----+++--++

Isolation, sampling and environmental information

isolation

@refsample typegeographic locationcountryorigin.countrycontinent
9347soilCaucasus regionRussiaRUSEurope
67770SoilCaucasusUSSR

isolation source categories

  • Cat1: #Environmental
  • Cat2: #Terrestrial
  • Cat3: #Soil

taxonmaps

  • @ref: 69479
  • File name: preview.99_210.png
  • url: https://microbeatlas.org/index.html?action=taxon&taxon_id=90_15;96_102;97_109;98_120;99_210&stattab=map
  • Last taxonomy: Streptomyces
  • 16S sequence: AB184124
  • Sequence Identity:
  • Total samples: 112
  • soil counts: 103
  • aquatic counts: 1
  • animal counts: 6
  • plant counts: 2

Interaction and safety

risk assessment

@refbiosafety levelbiosafety level comment
185461German classification
93471Risk group (German classification)

Sequence information

Genome sequences

@refdescriptionassembly levelINSDC accessionNCBI tax IDscore
124043ASM3953543v1 assembly for Streptomyces cremeus JCM 4362contigGCA_0395354356688172.62
124043ASM4243090v1 assembly for Streptomyces cremeus JCM 4362scaffoldGCA_0424309056688170.98

16S sequences

@refdescriptionaccessionlengthdatabaseNCBI tax ID
20218Streptomyces cremeus strain JCM 4362 16S ribosomal RNA gene, partial sequenceAY9997441429nuccore66881
20218Streptomyces cremeus gene for 16S ribosomal RNA, partial sequence, strain: JCM 4362D44079120nuccore66881
20218Streptomyces cremeus gene for 16S rRNA, partial sequence, strain: NBRC 12760AB1841241464nuccore66881
124043Streptomyces cremeus strain JCM 4362 16S ribosomal RNA gene, partial sequence.MT7605201307nuccore66881

Literature

@ref: 9347

culture collection no.: DSM 40147, ATCC 19744, ATCC 19897, CBS 483.68, ETH 24195, IFO 12760, INA 815/54, ISP 5147, NBRC 12760, RIA 1025, JCM 4362, BCRC 11466, CBS 111.60, CGMCC 4.1625, IMET 43743, NCIMB 10030, NCIMB 9596, NRRL 3241, NRRL B-2583, VKM Ac-1844

straininfo link

  • @ref: 126262
  • straininfo: 37147

literature

topicPubmed-IDtitleauthorsjournalDOIyearmeshtopic2
Metabolism468714PS-5, a new beta-lactam antibiotic. I. Taxonomy of the producing organism, isolation and physico-chemical properties.Okamura K, Hirata S, Koki A, Hori K, Shibamoto N, Okumura Y, Okabe M, Okamoto R, Kouno K, Fukagawa Y, Shimauchi Y, Ishikura T, Lein J.J Antibiot (Tokyo)10.7164/antibiotics.32.2621979metabolism, biosynthesis
Metabolism727755[Synthetic medium for the biosynthesis of tobramycin].Motkova MO.Antibiotiki1978biosynthesis, biosynthesis, metabolism
Metabolism7469392[Obtaining mutants that yield tobramycin in a culture of the producer of a complex of aminoglycoside antibiotics, Streptomyces cremeus var. tobramycini var. nov. 2242].Siniagina OP, Lapchinskaia OA, Lavrova-Balashova MF, Nesterova TP, Ponomarenko VI.Antibiotiki1980metabolism, biosynthesis, biosynthesis, biosynthesis, Mutation
Enzymology9606498[Novel L-glutamate oxidase producing organisms: Streptomyces litmocidini and Streptomyces cremeus].Dodzin ME, Vinogradova KA, Kotova IB.Antibiot Khimioter1998enzymology, biosynthesis
Metabolism12369145[L-Glutamate oxidase from Streptomyces cremeus 510 MGU: growth media optimization for the enhancement of the producer fermentative activity].Vinogradova KA, Vlasova II, Sharkova TS.Antibiot Khimioter2002metabolism, biosynthesis
Enzymology12803043[L-Glutamate oxidase from Streptomyces cremeus 510 MGU: effect of nitrogen sources on enzyme secretion].Vinogradova KA, Vlasova II, Sharkova TS, Dodzin ME, Maksimov VN.Antibiot Khimioter2003enzymology, metabolism, biosynthesisMetabolism
Phylogeny24091604Streptomyces fukangensis sp. nov., a novel alkaliphilic actinomycete isolated from a saline-alkaline soil.Zhang YG, Wang HF, Liu Q, Hozzein WN, Wadaan MA, Cheng J, Chen YJ, Zhang YM, Li WJAntonie Van Leeuwenhoek10.1007/s10482-013-0045-82013Amino Acids/analysis, Bacterial Typing Techniques, Base Composition, Carbohydrates/analysis, China, Cluster Analysis, DNA, Bacterial/chemistry/genetics, DNA, Ribosomal/chemistry/genetics, Desert Climate, Fatty Acids/analysis, Microscopy, Electron, Scanning, Molecular Sequence Data, Phospholipids/analysis, Phylogeny, Quinones/analysis, RNA, Ribosomal, 16S/genetics, Sequence Analysis, DNA, *Soil Microbiology, Streptomyces/*classification/genetics/*isolation & purification/physiologyGenetics
Enzymology26278892The Cremeomycin Biosynthetic Gene Cluster Encodes a Pathway for Diazo Formation.Waldman AJ, Pechersky Y, Wang P, Wang JX, Balskus EP.Chembiochem10.1002/cbic.2015004072015Biosynthesis, Enzymes, Natural products, heterologous expression, Diazo Compounds, metabolism, Multigene Family, geneticsMetabolism
Metabolism26689788A nitrous acid biosynthetic pathway for diazo group formation in bacteria.Sugai Y, Katsuyama Y, Ohnishi Y.Nat Chem Biol10.1038/nchembio.19912016metabolism, metabolism, chemistry, chemistry, genetics
Metabolism29654174Cezomycin Is Activated by CalC to Its Ester Form for Further Biosynthesis Steps in the Production of Calcimycin in Streptomyces chartreusis NRRL 3882.Wu H, Liang J, Wang J, Liang WJ, Gou L, Wu Q, Zhou X, Bruce IJ, Deng Z, Wang Z.Appl Environ Microbiol10.1128/aem.00586-182018Oligomer, Calcimycin Biosynthesis, Cezomycin, Substrate-coa Ligase, enzymology, metabolism, analogs & derivatives, biosynthesis, metabolismEnzymology
Metabolism29654175Recycling of Overactivated Acyls by a Type II Thioesterase during Calcimycin Biosynthesis in Streptomyces chartreusis NRRL 3882.Wu H, Liang J, Gou L, Wu Q, Liang WJ, Zhou X, Bruce IJ, Deng Z, Wang Z.Appl Environ Microbiol10.1128/aem.00587-182018Divalent cations, Type Ii Thioesterase, Calcimycin Biosynthesis, Coa Derivatives, enzymology, biosynthesis, metabolism, metabolism, metabolismEnzymology
29867825Variation in Bat Guano Bacterial Community Composition With Depth.Newman MM, Kloepper LN, Duncan M, McInroy JA, Kloepper JW.Front Microbiol10.3389/fmicb.2018.009142018Chiroptera, Bats, Bacterial diversity, Bacterial Communities, Guano, Tadarida Brasiliensis
Genetics34087065Leveraging Microbial Genomes and Genomic Context for Chemical Discovery.Kountz DJ, Balskus EP.Acc Chem Res10.1021/acs.accounts.1c001002021genetics, analysis, analysis, Genome, Bacterial
Enzymology34821235A roadmap for metagenomic enzyme discovery.Robinson SL, Piel J, Sunagawa S.Nat Prod Rep10.1039/d1np00006c2021isolation & purification, methodsPhylogeny
35877742Two New Phenylhydrazone Derivatives from the Pearl River Estuary Sediment-Derived Streptomyces sp. SCSIO 40020.Liu W, Ma L, Zhang L, Chen Y, Zhang Q, Zhang H, Zhang W, Zhang C, Zhang W.Mar Drugs10.3390/md200704492022Streptomyces sp., marine natural products, Phenylhydrazones, Penzonemycins, Streptomyces, Alkaloids
40045995Mechanistic and structural insights into the itaconate-producing trans-aconitate decarboxylase Tad1.Zheng L, Li W, Christ M, Paczia N, Buckel W, Mais CN, Bolker M, Freitag J, Bange G.PNAS Nexus10.1093/pnasnexus/pgaf0592025
40540318Role of a FAD-dependent monooxygenase in diazo group functionalization of kinamycin in Streptomyces ambofaciens.Vicente CM, Boutilliat A, Hotel L, Paris C, Aigle B.Microbiology (Reading)10.1099/mic.0.0015762025Streptomyces, Natural product, Diazo Group, Fad-dependent Monooxygenase, Kinamycin, Streptomyces, Flavin-Adenine Dinucleotide, Mixed Function Oxygenases

Reference

@idauthorscataloguedoi/urltitlejournalpubmed
9347Curators of the DSMZLeibniz Institut DSMZ-Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSM 40147)https://www.dsmz.de/collection/catalogue/details/culture/DSM-40147
18546Wink, J.http://www.dsmz.de/microorganisms/wink_pdf/DSM40147.pdfCompendium of Actinobacteria. HZI-Helmholtz-Centre for Infection Research, Braunschweig
20215Parte, A.C., Sardà Carbasse, J., Meier-Kolthoff, J.P., Reimer, L.C. and Göker, M.10.1099/ijsem.0.004332List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ
20216Curators of the HKIhttp://www.leibniz-hki.de/de/Collection Description Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie e. V. Hans-Knöll-Institut (HKI)
20218Verslyppe, B., De Smet, W., De Baets, B., De Vos, P., Dawyndt P.10.1016/j.syapm.2013.11.002StrainInfo introduces electronic passports for microorganisms.Syst Appl Microbiol. 37: 42-50 201424321274
67770Curators of the JCMhttps://jcm.brc.riken.jp/en/
68368Automatically annotated from API 20E
68382Automatically annotated from API zym
69479João F Matias Rodrigues, Janko Tackmann,Gregor Rot, Thomas SB Schmidt, Lukas Malfertheiner, Mihai Danaila,Marija Dmitrijeva, Daniela Gaio, Nicolas Näpflin and Christian von Mering. University of Zurich.https://microbeatlas.org/MicrobeAtlas 1.0 beta
124043Isabel Schober, Julia KoblitzData extracted from sequence databases, automatically matched based on designation and taxonomy
126262A. Lissin, I. Schober, J. F. Witte, H. Lüken, A. Podstawka, J. Koblitz, B. Bunk, P. Dawyndt, P. Vandamme, P. de Vos, J. Overmann, L. C. Reimer10.1093/database/baaf059StrainInfo—the central database for linked microbial strain identifiers

BacDive

About Team News Mailinglist

Help

How to cite Tutorials Contact Help

Social Media

BlueskyBluesky linkedin de.NBI Survey
DSMZ Global core biodata resource deNBI Elixis core data resource DZIF NFDI4 Biodiversity NFDI4 Microbiota
© DSMZ 2026 Imprint Privacy Statement Copyright & License License